Prescription Options

Combined Contraceptive Injections

July 10, 2018

A joint contraceptive injection is a monthly birth control shot that includes the combination of estrogen and progestin. Like Depo-Provera as well as the Noristerat shot, combined contraception injections are a type of hormonal birth control. Some of those injections comprise Cyclofem, Lunelle, and Mesigyna.

When to Have Your Injection

Monthly combined contraceptive shots are extremely much like combination birth control pills.

The estrogen and progestin hormones are injected into the muscle of your upper arm, thigh, or buttocks. After every injection, the hormone levels peak and then gradually decrease until the next injection.

In order to work, you must find a combined contraceptive injection every 28 to 30 days, and you can’t go beyond 33 days from the date of your last injection. When you get your shot within this interval, combined contraceptive injections have a failure rate of between less than one percent to 6 percent each year. This means they are 94 percent to 99 percent effective at preventing pregnancy.

How the Injections Function

The hormones delivered with a joint contraceptive injection chiefly work to prevent pregnancy for one month by:

  • preventing you from ovulating (releasing an egg).
  • Thickening your cervical mucus making it more difficult for sperm to swim through.
  • Thinning the lining of the uterus making it harder for implantation to take place.

    It’s also believed that monthly joint shots may offer added non-contraceptive health benefits. If you get pregnant when on your own joint contraceptive injection, this birth control shot will not hurt your baby.

    It will also not induce your pregnancy to terminate. After stopping your joint contraceptive injection, there might be a delay in regaining fertility, meaning your ability to get pregnant.

    Your fertility, but should return in a month or two after your last injection.

    Side Effects

    Since they’re so similar to other combination hormonal methods like the pill, the patch, and NuvaRing, combined contraceptive shots will generally have the same types of unwanted effects. Monthly combined shots contain less progestin than Depo-Provera and Noristerat, which are progestin-only contraceptive shots.

    If you use combination contraceptive shots, compared to progestin-only injections, you:

    • Are not as inclined to have spotting/irregular bleeding.
    • Have a lower prospect of amenorrhea (not using a span ).
    • Are more inclined to have a normal bleeding pattern and less bleeding side effects.

    Types of Injections

    Lunelle has been a monthly combined injection made up of pre-filled estradiol cypionate and medroxyprogesterone syringes. It became available in the USA in 2000. The Lunelle syringes were voluntarily recalled in 2002 because of concern over strength and potential danger of contraceptive failure. In October 2003, Pfizer ceased making Lunelle, therefore it’s no longer available in the USA.

    A similar joint contraceptive injection is currently sold under the title Cyclofem (also known as Lunelle, Cyclofemina, Feminena, Novafem, Lunella, and Cyclo-Provera).

    It’s available mostly in Latin America, Africa, and Asia, but you can’t get it in the United States. 

    Mesigyna (also called Norigynon, Mesigyna Instayect, Mesygest, and No 3 injectable Norigynon) is another kind of combined contraceptive injection. It consists of estradiol valerate and norethisterone enanthate. It just as powerful as Cyclofem, however, it’s also not available in the United States. Mesigyna is mostly available in Latin America and Asia.