The Difference Between Gardasil and Cervarix

October 7, 2018

If you or your child is supposed to acquire the HPV vaccine, a shot which helps to protect against many different strains of a ubiquitous organism known as human papillomavirus, you may have discovered there are two brands of this vaccine: Gardasil and Cervarix. Are they very different? And can you select which you get?

Yes rather than exactly. The two vaccines do protect against different strains of HPV (there are hundreds), a virus that is passed from person to person during all types of sexual contact, including intercourse, oral sexual intercourse, and anal intercourse, and is connected to several kinds of cancer.

Not all strains of HPV are associated with these diseases, however, which explains why HPV vaccines have been made to zero in on the ones that are most aggressive–HPV 16 and 18, according to the American Cancer Society.

Can You Have a Choice?

Regarding the question of picking that shot you purchase, that is different. For a few years both Gardasil, that is produced by the pharmaceutical company Merck, also Cervarix, made by GlaxoSmithKline (GSK), were offered in the USA. But, Cervarix wasn’t able to keep up with Gardasil with regards to earnings, and so in late 2016 GSK stopped making it at the U.S. It’s still available in different nations, such as those who constitute Europe, nonetheless. Cervarix is the first and only HPV vaccine to be accepted in China.

At the same time, it’s important to be aware that if you hear the name Gardasil, the vaccine being known isn’t the original one that made its debut in 2007.

The original Gardasil was designed to safeguard against four strains of HPV (why it was referred to as a quadrivalent vaccine). In December 2014, the U.S. Food and Drug Administration (FDA) approved a new version of Gardasil that shields against nine strains of HPV. It’s officially called Gardasail-9, but it is likely your doctor will simply say he’s giving you a dose of Gardasil when you move in for your shot.

Considering that the quadrivalent type of Gardasil is not accessible any longer, the comparisons that follow are of Gardasil-9 and Cervarix.


The HPV strains it protects against: HPV 6, 11, 16, 19, 31, 33, 45, 52, and 58. The first homed in on HPV 6, 11, 16, and 18; HPV 16 and HPV 18 are the two most aggressive ones, and also the only strains that Cervarix is concentrates on (see below).

1 thing to note: There’s information to indicate that Gardasil-9 and Cervarix can offer cross-protection against other HPV strains; however, they do not shield against any you may have been infected with.

Dosing program: Gardasil-9 is provided in three different doses over the course of six months. The next shot is awarded two months following the first, and the final dose is given four months after that.  It is necessary to get all three shots for the vaccine to have maximum efficiency.

Who it is for: On its website, the FDA says that Gardasil-9 is suggested for girls and women ages  to stop cervical, vulvar, vaginal, and anal cancer; and genital warts caused by HPV types 6 and 11, as well as numerous precancerous lesions. It’s also indicated in boys and men ages 9 through 26 for preventing rectal cancer brought on by HPV types 16, 18, 31, 33, 45, 52, and 58, in addition to genital warts and precancerous rectal lesions.


The HPV breeds it shields : HPV 16 and 18

Dosing schedule: Like Gardasil-9, Cervarix is given in 3 doses–the second one month following the first and the third five weeks after that. All three shots are necessary to find the most protection.

Who it’s for: Cervarix is FDA-approved for girls and women ages 9 to 25 to stop cervical cancer. 

Security Problems and/or Negative Effects

One of the problems that often comes up in discussions of any of the HPV vaccines is whether or not they’re safe. All three vaccines may have mild to moderate side effects such as inflammation and pain at the injection site, in addition to headaches, stomach aches, and other symptoms that are senile.

But they’re regarded as very safe.

Although more severe side effects are reported to the vaccine adverse event reporting system from people who have obtained the HPV shot, these have been demonstrated to not have been associated with this vaccine. Have, by and large, not been shown to be vaccine-related, as well as also the reports of vaccine-linked fatalities appear to be unfounded.